![]() Median ICU stay length was also longer for A or AB patients compared with O or B patients (13.5 days vs 9 days, P=0.03). O genes (or alleles) do not produce antigens A or B, thereby are called silent alleles. Inheritance Patterns The ABO gene found on chromosome 9 determines the ABO blood group system. Similar figures were seen for patients requiring continuous renal replacement therapy (32% vs 9%, P=0.04). O positive blood type is about 37 in Caucasians, 47 in African American, 53 in Hispanic, and 39 in Asian. A significantly higher proportion of A/AB patients required mechanical ventilation versus O/B patients (84% vs 61%, respectively, P=0.02). 21 to April 28, identifying 95 COVID-19 patients admitted to an ICU with known ABO blood type.Īmong these patients, 57 were group O or B, while 38 were group A or AB. They collected data from six metropolitan Vancouver hospitals from Feb. "If ABO blood groups play a role in determining disease severity, these differences would be expected to manifest within multiple organ systems and hold relevance for multiple resource-intensive treatments, such as mechanical ventilation and continuous renal replacement therapy," Sekhon and colleagues wrote. ![]() These authors also cited research that found that blood groups were linked to virus susceptibility, but that the relationship between SARS-CoV-2 infection severity and blood groups remains "unresolved." However, COVID-19 appears to be a multisystem disease with renal and hepatic manifestations. Researchers also observed how blood groups are "increasingly recognized to influence susceptibility to certain viruses," among them SARS-CoV-1 and norovirus, adding that individuals with A, B, and AB blood types may be at "increased risk for thrombosis and cardiovascular diseases," which are important comorbidities among patients hospitalized with COVID-19.ĪBO and RhD blood group information was available for 473,654 individuals who were tested for SARS-CoV-2 from February 27 to July 30, as well as for 2,204,742 individuals not tested for SARS-CoV-2 as a reference. ![]() They pointed to the recent research that blood type plays a role in infection, noting the lower than expected prevalence of blood group O individuals among COVID-19 patients. Limitations to the data include that ABO blood group information was only available for 62% of individuals, and that the sex of the testing population was skewed, with women accounting for 71% who tested negative and 67% who tested positive. ![]() However, there was no increased risk for COVID-19 hospitalization or death associated with blood type, the authors wrote in Blood Advances. ![]()
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